DIFFERENCES IN NEUTRALIZING ANTIBODY LEVELS TO BOVINE HERPESVIRUSES TYPES 1 (BHV-1) AND 5 (BHV-5)
Keywords:
Serum neutralization, Bovine Herpesviruses, BHV-1, BHV-5.Abstract
In order to compare the neutralizing antibody response after natural bovine herpesvirus infections, 508 cattle sere were tested by serum neutralization (SN) against bovine herpesvirus type I (BHV-1) and bovine herpesvirus type 5 (BHV-5). Two hundred. and forty-nine (49%) sere were negative for antibodies to both viruses, whereas 290 (57%) were positive for BHV-I and 288 (57%) were positive for BHV-5 antibodies. However, 41 (8%) of the BHV-1-positive sera were negative for BHV-5 antibodies. On the other hand, 39 (7.7%) of the BHV-5-positive sere were negative for BHV-1 antibodies. These resulta indicate that, if SN is to be used to evaluate the serological status of herda to thcse two types of viruses, testa must be performed against both BHV-1 and BHV-5, since they do not induce fully crossreactive neutralizing antibodics.
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